CPHON Certified Pediatric Hematology Oncology Nurse Exam Study Guide 2026-2027

CPHON Certified Pediatric Hematology Oncology Nurse Exam Study Guide 2026-2027

Exam Prep with 3 Full-Length Practice Tests, Detailed Answer Explanations, and Complete Review

By Capra Academy · Published May 20, 2026 · 465 pages

About This Book

Comprehensive CPHON certification review covering pediatric hematologic disorders, leukemias, lymphomas, CNS tumors, solid tumors, chemotherapy, biotherapy, immunotherapy, radiation therapy, surgical management, stem cell transplantation, and supportive care. Includes developmental, psychosocial, and end-of-life care topics. Three full-length practice exams.

What’s Inside

  • Three Full-Length Practice Exams
  • Pediatric Hematologic Disorders
  • Leukemias, Lymphomas & CNS Tumors
  • Chemotherapy, Biotherapy & Immunotherapy
  • Supportive Care & Oncologic Emergencies
  • Developmental & Psychosocial Care

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Frequently Asked Questions

What is the CPHON certification?

The CPHON (Certified Pediatric Hematology Oncology Nurse) is administered by ONCC (Oncology Nursing Certification Corporation). It validates specialized knowledge in caring for children and adolescents with hematologic and oncologic conditions.

How many questions are on the CPHON exam?

The CPHON exam has 165 multiple-choice questions (125 scored, 40 unscored) with a 3-hour time limit. The passing score is 55 on a scaled score range of 25-75. The exam costs $300 for ONCC members and $420 for non-members.

What is the CPHON pass rate?

The 2024 overall pass rate for CPHON is 74%, with a first-time pass rate of 57%. The exam is administered at PSI testing centers (in-person only).

What is the DoubleTake option for CPHON?

For an additional $100 paid at initial registration, the DoubleTake option provides one free retake if you fail the exam on your first attempt, without paying the full fee again.

CPHON Resource Hub

Planning Your CPHON Preparation

Who this exam information is for

This page is for candidates considering or actively preparing for the CPHON Certified Pediatric Hematology Oncology Nurse. Use the linked exam resources to understand the credential, organize preparation, and identify the official requirements that must be confirmed before applying.

What to verify before scheduling

  • Current eligibility and application documentation
  • Current examination blueprint and domain weights
  • Fees, testing windows, identification, and accommodation rules
  • Question format, time limit, scoring, and score-report process
  • Retake, renewal, and continuing-education policies

A practical study strategy

Begin with the current official content outline. Rank every domain by both blueprint weight and personal confidence, then spend the most time where high weight and low confidence overlap. Use practice questions diagnostically: record the tested domain, why the correct answer is best, why each distractor is weaker, and what source resolves any uncertainty.

Strengths and limitations of this study guide

The Capra Academy guide is designed to combine structured review with practice and answer explanations, making it useful for identifying weak areas and rehearsing exam-style decisions. It is a study aid—not the certifying organization’s candidate handbook, not a guarantee of a passing result, and not a substitute for current official eligibility or policy information. Requirements can change, so follow the official sources linked throughout this resource cluster.

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